Having lived in California, then Missouri, then Oregon, and having visited friends and relatives in Tennesee, Pennsylvania, Minnesota, North and South Carolina, I can honestly say there is a distinct difference in the cultures of this country depending on the region, including the Midwest and The South. I don't know much about the Raleigh/Durham area where Chapel Hill is, I think, I've visited Charlotte and Ashland NC. I've never been to Indiana, but DH has family there. Do you want to live with southern-fried charm or humble midwesterners? Gross generalizations, I know.

Aside from the cultural differences, I always go to weather--do you want mild winters or do you like/not mind the cold? Summers in NC get really muggy. Can you handle it?

I personally need mountains and ocean near me or I get buggy. I'm no kind of flatlander. Are these things important?

Sorry, I'm not much help, not having been to either city. Do check the crime rates and the kinds of crime, though. Is meth a problem in either city? Burglaries and other crimes are rampant where there are meth epidemics.

Go to the homepages of each city and see what the cultural attractions are if those are important to you.

Also, find out the cost of living in each city. That's one of the main factors that had us choosing Portland over Seattle.

Anhata
www.familynaturally.com
Your Family's General Store, Naturally